Invention Grant
- Patent Title: Genetically modified lactate-consuming yeasts and fermentation processes using such genetically modified yeasts
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Application No.: US16333070Application Date: 2017-09-15
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Publication No.: US11111482B2Publication Date: 2021-09-07
- Inventor: Arlene M. Fosmer , Christopher K. Miller , Gregory Michael Poynter , Brian Jeffrey Rush , Jon Veldhouse
- Applicant: CARGILL, INCORPORATED
- Applicant Address: US MN Wayzata
- Assignee: CARGILL, INCORPORATED
- Current Assignee: CARGILL, INCORPORATED
- Current Assignee Address: US MN Wayzata
- International Application: PCT/US2017/051720 WO 20170915
- International Announcement: WO2018/053230 WO 20180322
- Main IPC: C12N9/02
- IPC: C12N9/02 ; C12N9/18 ; C12N15/74 ; C12P7/06 ; C12N9/04 ; C07K14/395 ; C12N9/34

Abstract:
The present invention relates to genetically modified yeasts that can use lactate as a carbon source to produce a fermentation product. In one aspect, the yeasts can consume gluconse and lactate simultaneously to produce ethanol. In one aspect, the genetically modified yeast is transformed to include a monocarboxylic/monocarboxylate transporter. In one aspect, the yeast can include one or more heterologous genes encoding lactate dehydrogenase (cytochrome) (EC 1.1.2.3 and/or 1.1.2.4).
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