Invention Grant
- Patent Title: Methods for scarless introduction of targeted modifications into targeting vectors
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Application No.: US16838621Application Date: 2020-04-02
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Publication No.: US11111504B2Publication Date: 2021-09-07
- Inventor: Susannah Brydges , Jose F. Rojas , Gregg S. Warshaw , Chia-Jen Siao
- Applicant: Regeneron Pharmaceuticals, Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Alston & Bird LLP
- Agent Yongjin Choi
- Main IPC: C12N15/85
- IPC: C12N15/85 ; C12N9/22 ; C12N15/10
Abstract:
Methods for introducing a scarless targeted genetic modification into a preexisting targeting vector are provided. The methods can use combinations of bacterial homologous recombination (BHR) and in vitro assembly to introduce such targeted genetic modifications into a preexisting targeting vector in a scarless manner.
Public/Granted literature
- US20200318134A1 METHODS FOR SCARLESS INTRODUCTION OF TARGETED MODIFICATIONS INTO TARGETING VECTORS Public/Granted day:2020-10-08
Information query
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