A vehicle control system includes a controller that detects a communication loss between a first vehicle and a second vehicle and/or a monitoring device in a vehicle system. The controller operationally restricts movement of the vehicle system based on the communication loss. The controller obtains or generates a transitional plan that designates operational settings for the first vehicle and/or the second vehicle based at least in part on a location of the first vehicle and/or the second vehicle. The controller selectively changes movement of the first vehicle and/or the second vehicle via the transitional plan to reduce a speed of the first vehicle and/or the second vehicle responsive to the communication loss being detected.