A method of V-By-One (VBO) signal processing for saving hardware resources, and a device and terminal thereof are provided. The method includes steps of: obtaining a plurality of VBO signals transmitted through data lanes respectively and having a same descrambling reset flag; resolving each of the VBO signals to obtain a valid data strobe signal; selecting one valid data strobe signal as a synchronization strobe signal and performing time-delay processing to obtain a delay strobe signal; and writing signals alternately into a first register and a second register under control of the synchronization strobe signal and reading signals alternately from the second register and the first register under control of the delay strobe signal based on the same descrambling reset flag.