Implementations of the present specification provide a method and device for handling a multi-tenant request. A request to access an application from a user device is received, wherein the request includes a user identifier and request data. Tenant information corresponding to the user identifier is determined based on a mapping relationship between the user device and a tenant. Type information of the application is determined based on the request data. A first identifier of the application is extracted from the request data based on the type information of the application. The first identifier is modified to a second identifier based on the tenant information. A new request is determined based on the second identifier. The new request is sent to the application.