An apparatus and method for coupled medical image formation and medical image signal recovery using a dual domain network is disclosed. The dual-domain network includes a first deep neural network (DNN) to perform signal recovery in a sensor signal domain and a second DNN to perform signal recovery in an image domain. A sensor signal is acquired by a sensor of a medical imaging device. A refined sensor signal is generated from the received sensor signal using the first DNN. A first reconstructed medical image is generated from the received sensor signal. A second reconstructed medical image is generated from the refined sensor signal generated by the first DNN. An enhanced medical image is generated based on the both the first reconstructed medical image and the second reconstructed medical image using the second DNN. The enhanced medical image generated by the second DNN is displayed.