Invention Grant
- Patent Title: Compositions and methods relating to salts of specialized pro-resolving mediators
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Application No.: US16535754Application Date: 2019-08-08
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Publication No.: US11135298B2Publication Date: 2021-10-05
- Inventor: Frank C. Sciavolino , Gary Mathias , Michael C. Van Zandt , Gunnar Erik Jagdmann, Jr. , Jessica J. Dworak
- Applicant: Thetis Pharmaceuticals LLC
- Applicant Address: US CT Branford
- Assignee: Thetis Pharmaceuticals LLC
- Current Assignee: Thetis Pharmaceuticals LLC
- Current Assignee Address: US CT Branford
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Munel Liberto, Esq.
- Main IPC: A61K47/54
- IPC: A61K47/54 ; A61K47/62 ; C07C59/42 ; C07C229/26 ; C07C237/12 ; C07C237/22 ; A61P1/06 ; A61P1/12 ; A61P29/00 ; A61P1/04 ; A61K31/202 ; A61K31/232 ; A61K38/03 ; A61K45/06 ; A61P1/00

Abstract:
The present invention relates to compounds of Formulas I-IV and compositions comprising same, including pharmaceutical compositions. The compounds of Formulas I-IV represent new salt forms of specialized pro-resolving mediators (“SPMs”) which include lipoxins, resolvins, protectins, and their aspirin-triggered counterparts. The SPM salts described here contain at least one or two SPM molecules ionically bound to at least one basic function that is provided by a scaffold as described in Formulas I-IV. Also provided are methods for pharmaceutical and non-pharmaceutical uses of such compounds and compositions describing same.
Public/Granted literature
- US20200179521A1 COMPOSITIONS AND METHODS RELATING TO SALTS OF SPECIALIZED PRO-RESOLVING MEDIATORS Public/Granted day:2020-06-11
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