Invention Grant
- Patent Title: Device for suppressing inflammation and hyperimmunity, and method for suppressing inflammation and hyperimmunity
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Application No.: US15768253Application Date: 2016-10-13
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Publication No.: US11135425B2Publication Date: 2021-10-05
- Inventor: Hirofumi Kai , Tsuyoshi Shuto , Ann Soten Mary Suico , Eiichi Araki , Tatsuya Kondo
- Applicant: NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY
- Applicant Address: JP Kumamoto
- Assignee: NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY
- Current Assignee: NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY
- Current Assignee Address: JP Kumamoto
- Agency: Hunton Andrews Kurth LLP
- Priority: JPJP2015-203033 20151014
- International Application: PCT/JP2016/080443 WO 20161013
- International Announcement: WO2017/065239 WO 20170420
- Main IPC: A61N1/36
- IPC: A61N1/36 ; A61N1/32 ; A61N1/04 ; A61N1/08 ; A61N2/00

Abstract:
Provided is a new means for suppressing inflammation or suppressing inflammatory cytokine production. Provided is a device in which a weak pulse current is passed through a living body or living tissue to suppress inflammation in the living body or the living tissue. This device is provided with a power supply means, and a current control means for receiving a supply of power to intermittently apply a direct current at prescribed intervals, and is configured such that the current control means includes a pulse width modulation control means, and the pulse width modulation control means generates a pulse wave that is a rectangular wave, and in which the time indicating a peak value for rising in one cycle of the pulse wave (“pulse duration”) is at least 0.1 millisecond, the peak value is 1.0-20 V, inclusive, and the duty ratio of the pulse wave is at least 5.5%.
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