- Patent Title: Processes for the preparation of aryl hydrocarbon receptor ligands
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Application No.: US16906363Application Date: 2020-06-19
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Publication No.: US11136318B2Publication Date: 2021-10-05
- Inventor: Martin Benedict Strack , Jasper Kaiser , Gnel Mkrtchyan , Wen-Chun Zhang
- Applicant: Noramco, LLC
- Applicant Address: US DE Wilmington
- Assignee: Noramco, LLC
- Current Assignee: Noramco, LLC
- Current Assignee Address: US DE Wilmington
- Agency: Alston & Bird LLP
- Main IPC: C07D417/06
- IPC: C07D417/06 ; C07D413/06 ; C07D403/06
Abstract:
The present disclosure relates to the preparation of methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate (ITE) and related compounds with high yield, purity, and scalability. The processes apply the use of a Weinreb amide intermediate as a scaffold for the preparation of ITE and structural analogs.
Public/Granted literature
- US20210009579A1 PROCESSES FOR THE PREPARATION OF ARYL HYDROCARBON RECEPTOR LIGANDS Public/Granted day:2021-01-14
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