- Patent Title: Fusion protein for improving protein expression from target mRNA
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Application No.: US16305080Application Date: 2017-05-30
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Publication No.: US11136361B2Publication Date: 2021-10-05
- Inventor: Takahiro Nakamura , Yusuke Yagi
- Applicant: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
- Applicant Address: JP Fukuoka
- Assignee: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
- Current Assignee: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
- Current Assignee Address: JP Fukuoka
- Agency: Myers Bigel, P.A.
- Priority: JPJP2016-120524 20160617
- International Application: PCT/JP2017/020076 WO 20170530
- International Announcement: WO2017/209122 WO 20171207
- Main IPC: C07K14/415
- IPC: C07K14/415 ; C07K14/435 ; C12N15/62 ; C12N15/85 ; C07K19/00
Abstract:
[Problem to be Solved] The object of the present invention is to develop a method of regulating a target RNA.
[Solution] There is provided a fusion protein comprising a functional domain which improves the protein expression level from mRNA and a PPR protein which can bind to a target mRNA in an RNA base-selective or RNA base sequence-specific manner.
[Solution] There is provided a fusion protein comprising a functional domain which improves the protein expression level from mRNA and a PPR protein which can bind to a target mRNA in an RNA base-selective or RNA base sequence-specific manner.
Public/Granted literature
- US20190309029A1 FUSION PROTEIN FOR IMPROVING PROTEIN EXPRESSION FROM TARGET mRNA Public/Granted day:2019-10-10
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