Invention Grant
- Patent Title: Antibodies and Fc fusion protein modifications with enhanced persistence or pharmacokinetic stability in vivo and methods of use thereof
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Application No.: US16572003Application Date: 2019-09-16
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Publication No.: US11136377B2Publication Date: 2021-10-05
- Inventor: Derry Roopenian , Gregory Christianson
- Applicant: THE JACKSON LABORATORY
- Applicant Address: US ME Bar Harbor
- Assignee: THE JACKSON LABORATORY
- Current Assignee: THE JACKSON LABORATORY
- Current Assignee Address: US ME Bar Harbor
- Agency: Nixon Peabody LLP
- Agent David S. Resnick; Mark J. FitzGerald
- Main IPC: C07K16/00
- IPC: C07K16/00 ; A61K47/54 ; A61K47/68 ; A61K39/00

Abstract:
In certain embodiments, this present invention provides antibodies and Fc fusion proteins with enhanced pharmacokinetics, such as biotinylated antibodies or biotinylated Fc fusion polypeptides.
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