Invention Grant
- Patent Title: (R)-selective nitroaldol reaction catalysed by proteins of the cupin superfamily
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Application No.: US16535862Application Date: 2019-08-08
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Publication No.: US11136604B2Publication Date: 2021-10-05
- Inventor: Kerstin Steiner , Mandana Gruber , Romana Wiedner , Helmut Schwab
- Applicant: PATHEON AUSTRIA GMBH & CO KG
- Applicant Address: AT Linz
- Assignee: PATHEON AUSTRIA GMBH & CO KG
- Current Assignee: PATHEON AUSTRIA GMBH & CO KG
- Current Assignee Address: AT Linz
- Agency: Pierce Atwood LLP
- Agent Raymond G. Arner
- Priority: EP14172208 20140612
- Main IPC: C12P13/00
- IPC: C12P13/00 ; C12N9/88
Abstract:
The present invention relates to a method for producing chiral β-nitro alcohol compounds. The invention relates in particular to an (R)-selective cupin-nitroaldolase, which enantioselectively can catalyze the Henry reaction, wherein an aldehyde or ketone compound is converted to the corresponding β-nitro alcohol compound in the presence of a nitroalkane compound and a cupin-nitroaldolase.
Public/Granted literature
- US20200040368A1 (R)-SELECTIVE NITROALDOL REACTION CATALYSED BY PROTEINS OF THE CUPIN SUPERFAMILY Public/Granted day:2020-02-06
Information query
