Embodiments of the present invention disclose a security processing method and a related device. The method may include: receiving, by a base station, security-processed target data sent by user equipment UE; sending, by the base station, security request information of the UE to a core network device; and receiving, by the base station, security response information returned by the core network device, where the security response information includes security parameter information of the UE and/or security-deprocessed target data. According to the present invention, during data transmission between the UE and the base station, not only data security can be ensured, but also low power consumption can be ensured.