A method and a device for processing an image saturation based on depth of field, an electronic device and a computer readable storage medium are provided, for processing scene data collected by an imaging device. The scene data includes a first scene image. The method includes the following. The scene data is processed to determine whether a portrait exists in a scene. In response to determining that the portrait exists, the scene data is processed to identify a portrait region. The first scene image is processed to reduce a saturation of the portrait region.