- Patent Title: Soft neural electrode based on three-dimensional porous graphene foam material and use of three-dimensional porous graphene foam material to prepare bone defect filler
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Application No.: US16320141Application Date: 2017-05-10
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Publication No.: US11145850B2Publication Date: 2021-10-12
- Inventor: Judong Luo , Qi Zhang , Yuyou Qiu , Shuyu Zhang , Qin Song , Guangyu Tang , Jianping Cao , Hua Jiang
- Applicant: SOOCHOW UNIVERSITY
- Applicant Address: CN Suzhou
- Assignee: SOOCHOW UNIVERSITY
- Current Assignee: SOOCHOW UNIVERSITY
- Current Assignee Address: CN Suzhou
- Agency: SZDC Law PC
- Priority: CN201610453656.8 20160622,CN201610598554.5 20160728
- International Application: PCT/CN2017/083737 WO 20170510
- International Announcement: WO2017/219776 WO 20171228
- Main IPC: H01M4/133
- IPC: H01M4/133 ; A61N1/05 ; H01M4/80 ; A61L27/56

Abstract:
The invention provides a neural electrode, including a current generation device, a first and a second electrode. The current generation device is connected to the first and second electrodes through a conductive metal wire respectively. At least one of the first and second electrodes is a graphene electrode. The graphene electrode has soft texture and desirable stability to tolerate the repeated pressing and folding treatment, very high charge injection efficiency, and desirable in vivo stability, and is configured to electrically stimulate tissues and organs such as hearts and nerves to promote electrical stimulation and repair of neurons, to further promote regeneration of neural functions. The invention further provides use of a mineralized three-dimensional porous graphene foam material to prepare a bone defect filler. The bone defect filler has desirable biological compatibility, promotes cell proliferation, and accelerates and induces osteogenic differentiation of bone marrow mesenchymal stem cells.
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