An embodiment of the invention may include a method, computer program product and computer system for image artifact removal. The method, computer program product and computer system may include computing device which may receive a primary image and analyze the primary image for global artifacts and local artifacts. The computing device may, in response to identifying a global artifact in the primary image, generate a secondary image with the global artifact removed utilizing a first generative adversarial network. The computing device may, in response to identifying a local artifact in the primary image, generate a patch with the local artifact removed utilizing a second generative adversarial network. The computing device may generate a hybrid image containing a reduction of global artifacts and a reduction of local artifacts by combining the secondary image and the patch utilizing a hybrid generative adversarial network.