A cargo area door control system for a vehicle is provided. The vehicle includes at least one cargo area and at least one cargo area door configured to be movable to enable physical access to the at least one cargo area, and movable to block physical access to the at least one cargo area. The control system includes one or more processors and a memory communicably coupled to the one or more processors. The memory stores a cargo area door control module including instructions that when executed by the one or more processors cause the one or more processors to determine if the vehicle currently resides at a selected destination and, responsive to a determination that the vehicle currently resides at the selected destination, operate a cargo area door unlocking mechanism to unlock the at least one cargo area door.