Systems and methods related to calibrating a phase interpolator by amplifying timing differences are described. An example system includes a calibration stage configured to output a calibration code for a phase interpolator. The system further includes control logic configured to: (1) at least partially discharge a first pre-charged capacitive load in response to a signal output by the phase interpolator based on the calibration code, and (2) at least partially discharge a second pre-charged capacitive load in response to a reference signal associated with the phase interpolator. The system further includes a feedback path configured to provide feedback to the calibration stage to allow for a modification of the calibration code, where the feedback is dependent on a first voltage provided by the first pre-charged capacitive load and a second voltage provided by the second pre-charged capacitive load.