The present invention relates to technical field of communications and provides a method and a device for site selection for a monitoring station. The method comprises acquiring a site list comprising multiple relay stations and a connection relationship of optical cables among the relay stations; sequentially setting each relay station to be a starting site, and traversing the relay stations in the site list according to a preset coverage range from the starting site, and determining a set of uncovered relay stations corresponding to each starting site; according to a preset intersection base, traversing the set of relay stations that cannot be covered corresponding to each starting site to get an intersection, and determining one or more relay stations corresponding to a set of whose intersection result is empty as a target monitoring station. The method improves efficiency and accuracy of site selections and has wide applicability.