A method and a computing device for adjusting a region of interest (ROI) are provided. The method includes: receiving a image sequence including a current image and a previous image; generating a predefined searching area based on a previous ROI in the previous image; performing feature matching on multiple image features within the predefined searching area in the previous image and multiple image features within the predefined searching area in the current image; and adjusting a position of the previous ROI in the previous image based on the image features within the predefined searching area in the current image in response to that the image features within the predefined searching area in the current image satisfy a matching condition to obtain the current ROI in the current image.