Disclosed herein are related to a system and a method for synchronizing signal processing on audio channels. In one aspect, a system includes processors, each including an audio data input configured to receive audio data from multiple audio sources. In one aspect, each processor includes audio channels coupled to the audio data input, where each audio channel includes a corresponding processing chain configured to convert a sample rate of audio data from a corresponding audio source. Each processor may include a synchronization pulse generator configured to generate a corresponding synchronization pulse for each processing chain in response to a trigger pulse. The synchronization pulse generator may include a counter configured to generate an output having a phase based on a programmable initial condition of the counter, where the synchronization pulse for each processing chain is based on the counter output and a phase register value of the corresponding processing chain.