A method of replacing cables in a cable-driven surgical tool includes accessing a cable system of the cable-driven surgical tool, the cable-driven surgical tool including a shaft and an end effector operatively coupled to the distal end of the shaft. The cable system comprises distal and proximal cable portions extending within the shaft and adjoined by a releasable interconnect, the distal cable portion being operatively coupled to the end effector. The distal and proximal cable portions are disconnectable at the releasable interconnect, wherein the distal cable portion exhibits a first diameter and the proximal cable portion exhibits a second diameter greater than the distal cable portion. The distal cable portion is then removed and replaced with a replacement distal cable portion mated to the proximal cable portion.