Invention Grant
- Patent Title: Pharmaceutical active ingredient and use thereof, in particular for the prevention and treatment of metabolic disorders in humans and animals
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Application No.: US16486381Application Date: 2018-02-13
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Publication No.: US11191744B2Publication Date: 2021-12-07
- Inventor: Sebastien Peltier , Vivien Chavanelle , Florian Le Joubioux , Pascal Sirvent , Thierry Maugard
- Applicant: VALBIOTIS , UNIVERSITE CLERMONT AUVERGNE , UNIVERSITE DE LA ROCHELLE , CNRS
- Applicant Address: FR Perigny; FR Clermont Ferrand; FR La Rochelle; FR Paris
- Assignee: VALBIOTIS,UNIVERSITE CLERMONT AUVERGNE,UNIVERSITE DE LA ROCHELLE,CNRS
- Current Assignee: VALBIOTIS,UNIVERSITE CLERMONT AUVERGNE,UNIVERSITE DE LA ROCHELLE,CNRS
- Current Assignee Address: FR Perigny; FR Clermont Ferrand; FR La Rochelle; FR Paris
- Agency: Greer, Burns & Crain, Ltd.
- Priority: FR1770144 20170216
- International Application: PCT/EP2018/053520 WO 20180213
- International Announcement: WO2018/149812 WO 20180823
- Main IPC: A61K31/216
- IPC: A61K31/216 ; A61K31/7048 ; A61P3/00 ; A61P3/04 ; A61P3/06 ; A61P3/10

Abstract:
The invention relates to an active pharmaceutical ingredient consisting exclusively of the combination of (1S,3R,4R,5R)-3-{[(2E)-3-(3,4-)dihydroxyphenyl)-2-propenoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylic acid and of methyl (2S,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-2H-pyran-5-carboxylate for use as a drug or veterinary product, particularly in the prevention and/or treatment of pathological disorders of carbohydrate and/or lipid metabolism.
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