- Patent Title: Dosing and effect of C5a antagonist with ANCA-associated vasculitis
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Application No.: US16433487Application Date: 2019-06-06
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Publication No.: US11191756B2Publication Date: 2021-12-07
- Inventor: Jun Deng , Petrus Bekker , Jan Hillson
- Applicant: CHEMOCENTRYX, INC.
- Applicant Address: US CA Mountain View
- Assignee: CHEMOCENTRYX, INC.
- Current Assignee: CHEMOCENTRYX, INC.
- Current Assignee Address: US CA Mountain View
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo PC
- Main IPC: A61K31/445
- IPC: A61K31/445 ; A61K9/00 ; A61K31/675 ; A61K31/573 ; C07K16/28
Abstract:
The present disclosure provides methods for treating ANCA-associate vasculitis in a human in need thereof, the method comprising administering to the human a therapeutically effective amount of avacopan: or a pharmaceutically acceptable salt thereof, such that the level of plasma complement factor Bb, C3a, or C5a does not significantly change in the human upon treatment.
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