Invention Grant
- Patent Title: Cytocidal agent
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Application No.: US16960417Application Date: 2018-12-28
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Publication No.: US11191804B2Publication Date: 2021-12-07
- Inventor: Kazuhiro Sugihara , Naohiro Kanayama , Toshiaki Shibata , Yuichiro Onodera
- Applicant: FUJITA ACADEMY
- Applicant Address: JP Aichi
- Assignee: FUJITA ACADEMY
- Current Assignee: FUJITA ACADEMY
- Current Assignee Address: JP Aichi
- Agency: Lathrop GPM LLP
- Agent Brian C. Trinque; Rebecca Wright
- Priority: JPJP2018-001063 20180109
- International Application: PCT/JP2018/048523 WO 20181228
- International Announcement: WO2019/138944 WO 20190718
- Main IPC: A61K38/10
- IPC: A61K38/10 ; A61K47/64 ; A61P35/00 ; A61P43/00 ; C07K7/08
Abstract:
An object of the present invention is to provide a peptide drug that is able to selectively induce apoptosis in target cells. The present invention is a cytocidal agent containing a fusion peptide of an endosome escape peptide and an apoptosis-inducing peptide, which consists of an amino acid sequence represented by SEQ ID NO: 1, and the said cytocidal agent as a therapeutic agent for a disease caused by abnormal proliferation of cells.
Public/Granted literature
- US20200330549A1 CYTOCIDAL AGENT Public/Granted day:2020-10-22
Information query
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