Invention Grant
- Patent Title: Compositions and methods relating to salts of specialized pro-resolving mediators
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Application No.: US15733138Application Date: 2018-11-28
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Publication No.: US11191840B2Publication Date: 2021-12-07
- Inventor: Frank C. Sciavolino , Gary Mathias , Michael C. Van Zandt , Gunnar Erik Jagdmann, Jr. , Jessica J. Dworak
- Applicant: Thetis Pharmaceuticals LLC
- Applicant Address: US CT Branford
- Assignee: Thetis Pharmaceuticals LLC
- Current Assignee: Thetis Pharmaceuticals LLC
- Current Assignee Address: US CT Branford
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Muriel Liberto, Esq.
- International Application: PCT/US2018/062784 WO 20181128
- International Announcement: WO2019/108605 WO 20190606
- Main IPC: A61K47/54
- IPC: A61K47/54 ; A61K47/62 ; C07C59/42 ; C07C229/26 ; C07C237/12 ; C07C237/22 ; A61P1/06 ; A61P1/12 ; A61P29/00 ; A61P1/04 ; A61K31/202 ; A61K31/232 ; A61K38/03 ; A61K45/06 ; A61P1/00
Abstract:
The present invention relates to compounds of Formulas I-IV, which are salts of special lipid mediators of inflammation, compositions containing same, and methods of using same in the treatment of various diseases and disorders characterized by chronic or excessive inflammation, or both. Provided are pharmaceutical compositions adapted to deliver the compounds the lower gastrointestinal tract and methods of using same as monotherapy in the treatment of inflammatory diseases or disorders of the lower gastrointestinal tract, and in combination therapy with 5-aminosalicylate.
Public/Granted literature
- US20210138072A1 COMPOSITIONS AND METHODS RELATING TO SALTS OF SPECIALIZED PRO-RESOLVING MEDIATORS Public/Granted day:2021-05-13
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