Invention Grant
- Patent Title: Methods of inducing responsiveness to anti-angiogenic agent
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Application No.: US16505130Application Date: 2019-07-08
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Publication No.: US11191848B2Publication Date: 2021-12-07
- Inventor: Andrea Rachel Leubitz , Naamit Sher , Erez Feige , Eyal Breitbart
- Applicant: Vascular Biogenics Ltd.
- Applicant Address: IL Modiin
- Assignee: Vascular Biogenics Ltd.
- Current Assignee: Vascular Biogenics Ltd.
- Current Assignee Address: IL Modiin
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K38/17
- IPC: A61K38/17 ; A61K38/19 ; A61K39/00 ; A61K48/00 ; C07K14/705 ; C07K16/22 ; A61K39/395

Abstract:
The invention provides methods of inducing or improving responsiveness to a VEGF antagonist to a subject or a subject population comprising administering an adenovirus comprising a nucleic acid construct comprising a F AS-chimera gene operably linked to an endothelial cell-specific promoter and administering the VEGF antagonist.
Public/Granted literature
- US20200046852A1 METHODS OF INDUCING RESPONSIVENESS TO ANTI-ANGIOGENIC AGENT Public/Granted day:2020-02-13
Information query
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