Invention Grant
- Patent Title: Compositions and methods for inhibiting cancer stem cells
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Application No.: US15764629Application Date: 2016-09-29
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Publication No.: US11192948B2Publication Date: 2021-12-07
- Inventor: Elaine M. Hurt , Ralph Minter , Steven Rust , Alan Sandercock , Sotirios Karathanasis
- Applicant: MedImmune Limited
- Applicant Address: GB Cambridge
- Assignee: MedImmune Limited
- Current Assignee: MedImmune Limited
- Current Assignee Address: GB Cambridge
- International Application: PCT/EP2016/073362 WO 20160929
- International Announcement: WO2017/055511 WO 20170406
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/30 ; C12N5/095 ; G01N33/574 ; C12Q1/25 ; A61K31/713 ; A61K31/704 ; A61K39/00

Abstract:
The disclosure generally provides compositions and methods that are useful in the treatment of cancer. More specifically, the methods and compositions may be used to detect, quantify, inhibit, kill, differentiate, or eliminate cancer stem cells (CSCs) and may be used in the treatment of cancers associated with CSCs, and particularly cancers and CSCs that express LOX1.
Public/Granted literature
- US20180273616A1 COMPOSITIONS AND METHODS FOR INHIBITING CANCER STEM CELLS Public/Granted day:2018-09-27
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