- Patent Title: Compounds and methods for the treatment of TROP2 positive diseases
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Application No.: US16100995Application Date: 2018-08-10
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Publication No.: US11192954B2Publication Date: 2021-12-07
- Inventor: Weijia Tang , Xiaoyang Huang , Jin-Chen Yu , Ziqiang Ou , Xian Peng , Yili Yang , Shengfeng Li , Chao Qin
- Applicant: BIO-THERA SOLUTIONS, LTD.
- Applicant Address: CN Science City
- Assignee: BIO-THERA SOLUTIONS, LTD.
- Current Assignee: BIO-THERA SOLUTIONS, LTD.
- Current Assignee Address: CN Science City
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: CN201710687161.6 20170811
- Main IPC: C07K16/30
- IPC: C07K16/30 ; A61K47/68 ; A61P35/00 ; A61K39/00

Abstract:
The present invention generally relates to compounds comprising antibodies, antigen-binding fragments thereof, polypeptides, and immunoconjugates that bind to TROP2 (TACSTD2). The present invention also relates to methods of using such TROP2-binding molecules for diagnosing and treating diseases, such as malignancies.
Public/Granted literature
- US20190048095A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF TROP2 POSITIVE DISEASES Public/Granted day:2019-02-14
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