Invention Grant
- Patent Title: Monoclonal antibodies for use in diagnosis and therapy of cancers and autoimmune disease
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Application No.: US15895782Application Date: 2018-02-13
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Publication No.: US11192958B2Publication Date: 2021-12-07
- Inventor: Jeffrey Molldrem , Anna Sergeeva
- Applicant: Board of Regents, The University of Texas System
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K47/68 ; C07K16/28 ; C07K16/40 ; C07K16/30 ; A61K45/06 ; G01N33/574

Abstract:
The specification describes the sequences for antibodies that recognize the HLA-A2-restricted peptide PR-1 in the context of HLA presentation on the surface of cancer cells. Use of these antibodies in the diagnosis and treatment of cancer and immune-related diseases are also provided.
Public/Granted literature
- US20180371106A1 MONOCLONAL ANTIBODIES FOR USE IN DIAGNOSIS AND THERAPY OF CANCERS AND AUTOIMMUNE DISEASE Public/Granted day:2018-12-27
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