Invention Grant
- Patent Title: RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)
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Application No.: US15947248Application Date: 2018-04-06
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Publication No.: US11193126B2Publication Date: 2021-12-07
- Inventor: Mark Cancilla , James John Cunningham , William Michael Flanagan , Henry J. Haringsma , Denise M. Kenski , Matthew G. Stanton , Steven M. Stirdivant , Aarron T. Willingham
- Applicant: SIRNA THERAPEUTICS, INC.
- Applicant Address: US MA Cambridge
- Assignee: SIRNA THERAPEUTICS, INC.
- Current Assignee: SIRNA THERAPEUTICS, INC.
- Current Assignee Address: US MA Cambridge
- Agency: Lando & Anastasi, LLP
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/113 ; C12N15/11 ; A61K31/713

Abstract:
The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity, and/or modulate a gene expression pathway. Specifically, the invention relates to double-stranded nucleic acid molecules including small nucleic acid molecules, such as short interfering nucleic acid (siNA) molecules that are capable of mediating or that mediate RNA interference (RNAi) against target gene expression.
Public/Granted literature
- US20180362977A1 RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA) Public/Granted day:2018-12-20
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