Invention Grant
- Patent Title: Recombinant glycoproteins with reduced antennary fucosylation
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Application No.: US16496113Application Date: 2018-03-15
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Publication No.: US11193156B2Publication Date: 2021-12-07
- Inventor: Hanns-Martin Schmidt , Markus Ribbert , Gudrun Schiedner , Silke Wissing , Jens Wölfel
- Applicant: Cevec Pharmaceutical GmbH
- Applicant Address: DE Cologne
- Assignee: Cevec Pharmaceutical GmbH
- Current Assignee: Cevec Pharmaceutical GmbH
- Current Assignee Address: DE Cologne
- Agency: HelixIP LLP
- Priority: EP17000521 20170329
- International Application: PCT/EP2018/056502 WO 20180315
- International Announcement: WO2018/177758 WO 20181004
- Main IPC: C12N5/16
- IPC: C12N5/16 ; C12P21/00 ; C07K14/81 ; C12N9/10
Abstract:
The present invention relates to methods for reducing antennary fucosylation of complex N-glycans in recombinantly expressed glycoproteins, cell lines that can be used in said methods, respective recombinant glycoproteins, and methods for expressing the same in said cell lines.
Public/Granted literature
- US20200032311A1 Recombinant Glycoproteins with Reduced Antennary Fucosylation Public/Granted day:2020-01-30
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