Invention Grant
- Patent Title: Methods of diagnosing and treating cancer targeting extrachromosomal DNA
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Application No.: US15989100Application Date: 2018-05-24
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Publication No.: US11193164B2Publication Date: 2021-12-07
- Inventor: Paul Mischel , Prashant Mali , Vineet Bafna , Kristen Turner , Viraj Deshpande , Doruk Beyter
- Applicant: The Regents of the University of California , Ludwig Institute for Cancer Research Ltd
- Applicant Address: US CA Oakland; CH Zurich
- Assignee: The Regents of the University of California,Ludwig Institute for Cancer Research Ltd
- Current Assignee: The Regents of the University of California,Ludwig Institute for Cancer Research Ltd
- Current Assignee Address: US CA Oakland; CH Zurich
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: C12Q1/6841
- IPC: C12Q1/6841 ; C12Q1/6886
Abstract:
Provided herein are, inter alia, methods and compositions to detect, monitor and treat cancer, wherein the cancer includes amplified extrachromosomal oncogenes. The methods are useful for personalized treatment and exploit differential expression of amplified extrachromosomal oncogenes in cancer cells versus healthy cells.
Public/Granted literature
- US20180355416A1 METHODS OF DIAGNOSING AND TREATING CANCER TARGETING EXTRACHROMOSOMAL DNA Public/Granted day:2018-12-13
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