Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may generate multiple orthogonal demodulation reference signal (DMRS) sequences associated with multiple orthogonal DMRS ports based at least in part on a pi/2 binary phase shift keying (BPSK) based DMRS base sequence and based at least in part on utilizing at least one of a frequency-domain comb structure or a time-domain orthogonal cover code (OCC), wherein the multiple orthogonal DMRS ports are associated with different UEs; determine a DMRS port, of the multiple orthogonal DMRS ports, to be used in association with a transmission of pi/2 BPSK modulated data; and transmit the pi/2 BPSK modulated data and a DMRS sequence, of the multiple orthogonal DMRS sequences, associated with the DMRS port. Numerous other aspects are provided.