A multi-headed camera assembly includes a base comprising a plurality of tracks, a plurality of image sensor assemblies each comprising a support mechanism configured to allow a quick and efficient assembly of a lens assembly within a housing and each removably coupled to the base by a corresponding support frame among a plurality of support frames. Each support frame comprises a guide member for guiding tilt movement of a corresponding image sensor assembly and a support base movably coupled to a corresponding track so as to accomplish pan movement of the corresponding image sensor assembly. The multi-headed camera assembly further includes a surface mount mechanism, an in-ceiling mount mechanism, or a pendant mount mechanism so that the multi-headed camera assembly can be removably mounted to a surface, mounted into a ceiling, or connected to a pendant base.