A system for controlling LED lightbox power supplies, comprises the lightbox supplies disposed inside a lightbox and correspondingly connected with LED light bars one by one. All the lightbox power supplies are connected in series with one another via a 485 communication bus. Meanwhile, a wireless communication device connected in series with the lightbox power supplies is further mounted inside the lightbox. A gateway device for wirelessly connecting with the wireless communication device and uploading data acquired to a cloud server, is arranged outside the lightbox. A sensor set connected in a wired manner with the wireless communication device is arranged on an outer wall of the lightbox.