A cable lead-through assembly (2) includes s frame (10) delimiting a cable reception space (20); and an in-frame sub-system (11) configured for securing cables (1) to the frame (10). The in-frame sub-system (11) includes at least two plates (32) intended for extending in said cable reception space (20), the plates (32) being configured for being coupled to the frame (10) and for forming between each other at least one cable's path for at least one cable (1); securing means (14) configured for securing the or each cable (1) to a corresponding plate (32); and a locking unit (16) coupled to the frame (10). The locking unit (16) has an at-rest configuration and an operational configuration. The locking unit (16) is configured for displacing the plates (32).