- Patent Title: Kinin-based theranostic probes for solid cancers and uses thereof
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Application No.: US15738671Application Date: 2016-06-23
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Publication No.: US11213597B2Publication Date: 2022-01-04
- Inventor: Fernand Gobeil , Brigitte Guerin , Martin Lepage , Robert Sabbagh , David Fortin
- Applicant: SOCIETE DE COMMERCIALISATION DES PRODUITS DE LA RECHERCHE APPLIQUEE SOCPRA SCIENCES SANTE ET
- Applicant Address: CA Sherbrooke
- Assignee: SOCIETE DE COMMERCIALISATION DES PRODUITS DE LA RECHERCHE APPLIQUEE SOCPRA SCIENCES SANTE ET
- Current Assignee: SOCIETE DE COMMERCIALISATION DES PRODUITS DE LA RECHERCHE APPLIQUEE SOCPRA SCIENCES SANTE ET
- Current Assignee Address: CA Sherbrooke
- Agency: Norton Rose Fulbright Canada LLP
- International Application: PCT/CA2016/050732 WO 20160623
- International Announcement: WO2016/205914 WO 20161229
- Main IPC: A61K51/08
- IPC: A61K51/08 ; C07K7/06 ; C07K7/18 ; A61K38/04 ; C07K1/13 ; G01N33/574 ; C07K14/72

Abstract:
It is provided new chemical entities allowing simultaneous diagnosis and treatment of cancers. More specifically, it is provided a theranostic compound consisting of a stabilized peptide ligand (agonists and antagonists) for the kinin B1 receptors (B1R) conjugated to specific radionuclides (e.g. 64Cu) suitable for dual imaging/radiotherapy applications.
Public/Granted literature
- US20180311385A1 NOVEL KININ-BASED THERANOSTIC PROBES FOR SOLID CANCERS AND USES THEREOF Public/Granted day:2018-11-01
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