Disclosed are a fuel door having a cap sealing structure which obviates a cap for urea solution or water injection and a vehicle including the same. The fuel door includes a protrusion configured to protrude from an inner side of the fuel door and comprising a hollow and at least one cutout part being in fluid communication with the hollow, a membrane member coupled to the protrusion so as to cover the hollow of the protrusion, and a sealing member installed on the protrusion along a circumference of the membrane member.