The present disclosure provides systems for refrigeration facility cooling and water desalination. In certain aspects, the systems include a refrigeration facility having a water cooling subsystem configured to receive cool water and output warm water and a desalination plant co-located with the refrigeration facility and configured to receive and desalinate the warm water. Aspects of the invention also include methods for cooling a refrigeration facility using a water cooling subsystem and desalinating water with a desalination plant that is co-located with the refrigeration facility.