A system for effectively removing biochemical oxygen demand (BOD), total suspended solids (TSS), ammonia, total nitrogen (TN), and total phosphorus (TP) from wastewater has integrated multiple physiochemical and biological treatment processes into one unit. This system includes a primary DAF unit, anoxic bio-media treatment zone, and a secondary DAF unit. The bio-media treatment zones may be used to remove BOD and TN and may be divided into a number of functional zones. Each functional zone can develop and accumulate optimized bacteria species and microorganisms based on incoming wastewater BOD and nutrient levels.