Invention Grant
- Patent Title: Dextrorphan prodrugs and processes for making and using them
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Application No.: US16604755Application Date: 2018-04-12
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Publication No.: US11214544B2Publication Date: 2022-01-04
- Inventor: Travis Mickle , Sven Guenther , Sanjib Bera
- Applicant: KEMPHARM, INC.
- Applicant Address: US IA Coralville
- Assignee: KEMPHARM, INC.
- Current Assignee: KEMPHARM, INC.
- Current Assignee Address: US IA Coralville
- Agency: McAndrews Held & Malloy, Ltd.
- International Application: PCT/US2018/027266 WO 20180412
- International Announcement: WO2018/191477 WO 20181018
- Main IPC: C07D221/28
- IPC: C07D221/28 ; A61K31/439 ; A61K47/54

Abstract:
The presently described technology provides compositions of one or more of oxoacids, polyethylene glycols, and/or vitamin compounds chemically conjugated to dextrorphan, (+)-17-methylmorphinan-3-ol), to form novel prodrugs and compositions of dextrorphan.
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