Invention Grant
- Patent Title: Anticancer peptides and uses thereof
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Application No.: US16753627Application Date: 2018-10-04
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Publication No.: US11214593B2Publication Date: 2022-01-04
- Inventor: Teresa Royo Bargués
- Applicant: SUIGENERIS FARMACOSMETICS, S.L.
- Applicant Address: ES Barcelona
- Assignee: SUIGENERIS FARMACOSMETICS, S.L.
- Current Assignee: SUIGENERIS FARMACOSMETICS, S.L.
- Current Assignee Address: ES Barcelona
- Agency: Squire Patton Boggs (US) LLP
- Priority: EP17382667 20171005
- International Application: PCT/EP2018/077033 WO 20181004
- International Announcement: WO2019/068822 WO 20190411
- Main IPC: A61K38/08
- IPC: A61K38/08 ; C07K7/06 ; A61K47/62 ; A61K38/00

Abstract:
The present invention provides a peptide of formula (I), or a pharmaceutically acceptable salt thereof, wherein the N-terminal group of the peptide is a monoradical of formula —NHR1; the C-terminal group of the peptide is a monoradical of formula —C(O)—R2; R1 is a monoradical selected from hydrogen and —C(O)—(C1-C20)alkyl; R2 is a monoradical selected from —OH and —NR3R4 radical; R3 and R4 are independently selected from hydrogen and (C1-C10)alkyl; “a” to “j” are integers from 0 to 1, provided that at least one of “a” to “j” is 1; and X1 represents any amino acid. The present invention also provides conjugates and compositions comprising the peptide of formula (I). The peptide can be used in the treatment or prevention of neoplastic diseases such as pancreatic cancer. CaCbCcCdCeFEX1SKYCfCgChCiCj (I)
Public/Granted literature
- US20200239520A1 ANTICANCER PEPTIDES AND USES THEREOF Public/Granted day:2020-07-30
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