The invention discloses a method for producing surfactin by using Bacillus amyloliquefaciens, belonging to the technical field of industrial microorganisms. The invention synthesizes surfactin by using the screened Bacillus amyloliquefaciens CGMCC No. 12593, the yield is up to 9.43 g/L, and a fermentation process has the characteristics that the surfactin synthesis and the growth of the strain are synchronous without a lag period. The strain and the fermentation method provided by the invention will play an important role in the industrial production of surfactin and have broad application prospects.