Invention Grant
- Patent Title: Assays for massively combinatorial perturbation profiling and cellular circuit reconstruction
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Application No.: US15965192Application Date: 2018-04-27
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Publication No.: US11214797B2Publication Date: 2022-01-04
- Inventor: Aviv Regev , Brittany Adamson , Brian Cleary , Le Cong , Atray Dixit , Jellert Gaublomme , Eric S. Lander , Thomas Norman , Oren Parnas , Orit Rozenblatt-Rosen , Alexander K. Shalek , Jonathan Weissman
- Applicant: The Broad Institute, Inc. , Massachusetts Institute of Technology , The Regents of the University of California
- Applicant Address: US MA Cambridge; US MA Cambridge; US CA Oakland
- Assignee: The Broad Institute, Inc.,Massachusetts Institute of Technology,The Regents of the University of California
- Current Assignee: The Broad Institute, Inc.,Massachusetts Institute of Technology,The Regents of the University of California
- Current Assignee Address: US MA Cambridge; US MA Cambridge; US CA Oakland
- Agency: Johnson, Marcou, Isaacs & Nix, LLC
- Agent F. Brent Nix, Esq.; Michael B. Scher, Esq.
- Main IPC: C12N15/10
- IPC: C12N15/10 ; G16B5/00 ; C12N9/22 ; C12N15/11 ; C12N15/113 ; C12Q1/6886
Abstract:
The present invention provides tools and methods for the systematic analysis of genetic interactions, including higher order interactions. The present invention provides tools and methods for combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.
Public/Granted literature
- US20190085324A1 ASSAYS FOR MASSIVELY COMBINATORIAL PERTURBATION PROFILING AND CELLULAR CIRCUIT RECONSTRUCTION Public/Granted day:2019-03-21
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