Invention Grant
- Patent Title: HA-specific influenza virus attenuated vaccine comprising mutations in segment 7, and uses therefor
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Application No.: US16814286Application Date: 2020-03-10
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Publication No.: US11214799B2Publication Date: 2022-01-04
- Inventor: Darrell R. Kapczynski , Paul Digard , Lonneke Vervelde , David L. Suarez
- Applicant: The United States of America, as Represented by the Secretary of Agriculture , The Roslin Institute, University of Edinburgh
- Applicant Address: US DC Washington; GB Edinburgh
- Assignee: The United States of America, as Represented by the Secretary of Agriculture,The Roslin Institute, University of Edinburgh
- Current Assignee: The United States of America, as Represented by the Secretary of Agriculture,The Roslin Institute, University of Edinburgh
- Current Assignee Address: US DC Washington; GB Edinburgh
- Agent John Fado; Maria Restrepo-Hartwig
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K48/00 ; A01N63/00 ; A01N65/00 ; A61K39/00 ; C12N15/11 ; C12N5/071 ; A61K39/145
Abstract:
The disclosure relates to mutant recombinant influenza virus gene segment 7 with at least one mutation that modulates expression of M2 and M42 polypeptide. Also disclosed are recombinant influenza viruses comprising the mutant influenza virus gene segment 7, compositions comprising the mutant recombinant influenza virus gene segment 7, use of such mutant recombinant influenza virus gene segment 7 and mutant recombinant Influenza viruses.
Public/Granted literature
- US20200291397A1 Influenza Virus Mutants and Uses Therefor Public/Granted day:2020-09-17
Information query
