- Patent Title: Recombinant microorganism having heterologous genes introduced thereto and method for producing useful material from formic acid and carbon dioxide using same microorganism
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Application No.: US16472876Application Date: 2017-11-20
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Publication No.: US11214816B2Publication Date: 2022-01-04
- Inventor: Sang Yup Lee , Junho Bang
- Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Daejeon
- Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Daejeon
- Agency: Hultquist, PLLC
- Agent Steven J. Hultquist
- Priority: KR10-2016-0180223 20161227,KR10-2017-0151642 20171114
- International Application: PCT/KR2017/013171 WO 20171120
- International Announcement: WO2018/124475 WO 20180705
- Main IPC: C12P1/04
- IPC: C12P1/04 ; C12N15/70 ; C12P13/04 ; C12P5/02 ; C12P7/04 ; C12P7/24

Abstract:
The present invention relates to a recombinant microorganism having heterologous genes introduced thereto and a method for producing a useful material from formic acid and carbon dioxide using the microorganism. The present invention provides a novel microorganism having a cyclic metabolic pathway introduced thereto through which C3 or higher carbon organic compounds can be synthesized from formic acid and carbon dioxide, whereby carbon dioxide rich in nature and formic acid that is of low toxicity and suitable for anabolic reaction in view of reaction kinetics and which can be easily and rapidly synthesized from carbon dioxide can be used to effectively synthesize the C3 organic compound pyruvic acid from which various high-value added compound can be synthesized.
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