Invention Grant
- Patent Title: Circulating microRNA signatures for ovarian cancer
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Application No.: US16476799Application Date: 2018-01-09
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Publication No.: US11214839B2Publication Date: 2022-01-04
- Inventor: Dipanjan Chowdhury , Kevin M. Elias , Wojciech Fendler , Konrad Stawiski
- Applicant: DANA-FARBER CANCER INSTITUTE, INC. , THE BRIGHAM AND WOMEN'S HOSPITAL, INC. , MEDICAL UNIVERSITY OF LODZ
- Applicant Address: US MA Boston; US MA Boston; PL Lodz
- Assignee: DANA-FARBER CANCER INSTITUTE, INC.,THE BRIGHAM AND WOMEN'S HOSPITAL, INC.,MEDICAL UNIVERSITY OF LODZ
- Current Assignee: DANA-FARBER CANCER INSTITUTE, INC.,THE BRIGHAM AND WOMEN'S HOSPITAL, INC.,MEDICAL UNIVERSITY OF LODZ
- Current Assignee Address: US MA Boston; US MA Boston; PL Lodz
- Agency: Lathrop GPM LLP
- Agent Brian C. Trinque
- International Application: PCT/US2018/012982 WO 20180109
- International Announcement: WO2018/129535 WO 20180712
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12Q1/6886 ; G16B40/00 ; G16B30/00 ; C12Q1/686

Abstract:
Provided herein are methods and kits for determining the presence or absence of certain microRNA biomarkers in a blood sample of a female patient. The microRNA biomarkers are associated with ovarian cancer. Also provided are methods for screening a female subject for the presence or absence of certain microRNA biomarkers, as well as methods for treating a female subject having an ovarian cancer.
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