Systems, devices, and techniques for determining downhole fluid contamination are disclosed. In one or more embodiments, phase-related properties are measured for a reservoir fluid having a determined composition. An equation-of-state (EOS) isselected and/or tuned based, at least in part, on the measured phase-related properties and the tuned EOS is applied to estimate fluid property values for a reference fluid over specified ranges of at least two thermodynamic properties. Contaminant reference data are generated that correlate the estimated fluid property values for the reference fluid with respective contaminant levels. Within a wellbore, a fluid sample is analyzed to determining a fluid property values. A contaminant level is identified that corresponds within the contaminant reference data to the determined fluid property value of the fluid sample.