- Patent Title: Multi-photon endomicroscope for vertical cross-sectional imaging
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Application No.: US16465558Application Date: 2017-12-04
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Publication No.: US11215805B2Publication Date: 2022-01-04
- Inventor: Kenn Oldham , Jongsoo Choi , Xiyu Duan , Thomas D. Wang , Haijun Li
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2017/064539 WO 20171204
- International Announcement: WO2018/102822 WO 20180607
- Main IPC: G02B26/08
- IPC: G02B26/08 ; G02B21/00 ; A61B1/00 ; A61B1/06 ; G02B26/10

Abstract:
A multi-photon optical probe includes a probe housing, a lateral scanning stage coupled to a lateral mirror assembly and a remote axial scanning stage coupled to an axial mirror assembly. The lateral scanning stage is adapted to scan output laser energy over a planar scan area of the sample by moving the lateral mirror assembly. The axial scanning stage is adapted to scan the output laser energy over a vertical depth range of the sample, which, combined with the planar scan area, forms a 3-dimensional volume. A controller operates in conjunction with a number of remote actuating legs coupled to the axial mirror assembly in order to provide level imaging plane which in turn provides for a clear scanned image.
Public/Granted literature
- US20200096753A1 Multi-Photon Endomicroscope for Vertical Cross-Sectional Imaging Public/Granted day:2020-03-26
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